Scientist Job at Eli Lilly in USA | Biochemistry Graduates Apply
Lilly is hiring a Scientist in Oligonucleotide Chemistry at its Innovation Center in Boston, Massachusetts. This full-time role offers an exciting opportunity to contribute to the next generation of RNA therapies through advanced research in synthetic chemistry and biotechnology. If you are passionate about innovation in drug discovery and want to work in a collaborative, dynamic environment, this position is your chance to make an impact on global healthcare.
- Job Position: Scientist – Oligonucleotide Chemistry
- Location: Boston, Massachusetts, USA
- Job ID: R-93269
About the Company:
Eli Lilly and Company (Lilly) is a global healthcare leader with over 140 years of innovation, making life better through groundbreaking medicines. Headquartered in Indianapolis, Indiana, Lilly unites caring with discovery. The scientist jobs at Lilly’s Boston Innovation Center focus on next-generation therapeutics, genetic medicine, and data-driven healthcare. Situated in the heart of Massachusetts’ science and technology hub, Lilly provides an ideal environment for those seeking a career as a scientist in biotechnology and healthcare innovation.
Qualifications:
To be eligible for this scientist job/Biochemistry job candidates must have:
- Bachelor’s or Master’s degree in biochemistry or a related field.
- Minimum 1 year of research experience (academic or industrial).
Job Description:
The Scientist – Oligonucleotide Chemistry Job involves joining Lilly’s Genetic Medicine team to design, synthesize, and analyze RNA oligonucleotide drug candidates. This exciting scientist role includes developing novel chemistries, using advanced instrumentation, and collaborating with multidisciplinary teams in neuroscience, diabetes, and immunology. It’s the perfect opportunity for candidates aiming to build a strong scientific career in RNA-based therapies.
Key Responsibilities:
In this scientist job, you will:
- Design and execute automated workflows for synthesizing and purifying ASOs, siRNAs, SSOs, and related oligonucleotides.
- Perform synthesis and purification of innovative phosphoramidite monomers and conjugate ligands to oligonucleotides for targeted delivery.
- Apply analytical techniques such as UV-Vis, NMR, HPLC, and LC-MS to evaluate synthetic compounds.
- Interpret, organize, and present research data to project teams.
- Support troubleshooting and contribute scientific insights to ongoing projects.
- Maintain accurate electronic lab notebooks and comply with Lilly’s quality standards.
- Assist in lab operations, including reagent preparation, supply ordering, and equipment maintenance.
- Collaborate with cross-functional teams within Lilly’s Genetic Medicine group.
- Strictly follow health and safety protocols.
- Promote diversity, equity, and inclusion in the laboratory environment.
Additional Skills:
To excel in this scientist position, you should bring
- Strong background in organic synthesis and chromatographic purification.
- Proficiency with HPLC, LC-MS, and analytical data interpretation.
- Experience in conjugation/bioconjugation chemistry, as well as solid-phase synthesis, is highly desirable.
- Strong communication, collaboration, and organizational skills.
- Ability to thrive in a fast-paced, innovative research environment.
- Proficiency in Microsoft Office and analytical software tools.
