Associate Scientist Biology at Agios Pharmaceuticals – Apply Now!
Who we are:
Agios is a biopharmaceutical company that is fueled by connections. We thrive in a supportive, fun, and flexible environment full of people empowered to bring their whole selves to work. We care deeply about our work, each other, and the patients who count on us. Our teams cultivate strong bonds with patient communities, healthcare professionals, partners and colleagues, which helps us discover, develop and deliver therapies for rare diseases โ and make a bigger difference in their lives. In the U.S., Agios markets a first-in-class pyruvate kinase (PK) activator for the treatment of hemolytic anemia in adults with PK deficiency. Building on the companyโs leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia.
Associate Scientist, Biology
Primary Work Location: Onsite – Cambridge, MA
Job Code: 2255
# of Openings: 1
The Impact You Will Make:
Agios Pharmaceuticals is seeking a dynamic Associate Scientist to join our Biology team within the Translational Research department. The ideal candidate is driven to fulfill our mission to develop novel treatments for patients with diseases with a high unmet medical need. The Associate Scientistโs contributions will be of high impact towards shaping the companyโs understanding of how unique therapeutic approaches can be applied to treat underserved indications as well as identifying additional indications which could benefit from treatment with existing assets. This includes developing cell-based assays aimed to elucidate the therapeutic mechanism of action and proof-of concept, as well as identifying key pharmacodynamic biomarkers, all of which will shape the design of in vivo studies and clinical trials.
What You Will Do:
- Represent Biology working in a multi-functional team of researchers, clinicians, and regulatory members with the common goal of advancing pre-clinical assets to IND filing.
- Optimization and validation of cell-based systems relevant to therapeutic target tissue to verify drugging strategy and elucidate mechanism of action.
- Evaluate and expand the use of available technologies towards the identification and quantitation of translatable biomarkers.
- Analyze and interpret data, synthesize conclusions and propose next steps to the working team.
What You Bring:
- MS or BA in Biology with 3+ years of experience in industry or 5+ years total professional experience.
- Strong track record of thoroughly documenting experiments in a lab notebook and the ability to analyze, illustrate and present data for discussion.
- Skilled in the isolation, culturing and treatment of cells as well as biomarker analysis using qPCR, western blotting and ELISA.
- Experienced user of Seahorse and FACS instruments.
- Background in cellular metabolism is preferable but not required.
Link to apply: APPLY ONLINE HERE
Keywords: Associate Scientist, Biology, Agios Pharmaceuticals, Cambridge, Massachusetts, Biopharmaceutical, Translational Research, Cell-Based Assays, Biomarker Analysis. Associate Scientist Biology at Agios Pharmaceuticals – Apply Now!
