AstraZeneca Hiring: Senior Role in Oligonucleotide Therapeutics in Sweden!
About AstraZeneca
Are you a quantitatively-minded scientist looking to apply bioinformatics and machine learning to design oligonucleotides for therapeutic use? At AstraZeneca, we turn ideas into life-changing medicines. Working here means thinking big and working together to deliver impact from our contributions that make the impossible a reality.
Location
Sweden – Gothenburg
Job Details
- Time Type: Full time
- Posted on: Posted Today
- Job Requisition ID: R-202914
Senior Bioinformatician for Oligonucleotide Therapeutics
We have an exciting opportunity to join our Data Sciences and Quantitative Biology team that works as part of the Discovery Sciences organisation, within BioPharma R&D and contribute as a Senior Bioinformatician for Oligonucleotide Therapeutics. This position will be based at our vibrant R&D site in Gothenburg, Sweden.
Discovery Sciences work with all AstraZeneca therapy areas to deliver candidate drugs into late-stage clinical development. The Data Sciences and Quantitative Biology team is a multi-disciplinary team of data scientists with the purpose of providing quantitative insights to biology. In partnership with our experimentalist colleagues, we provide computational analysis and solutions to enable and drive our drug discovery efforts forward.
What you will do
As Senior Bioinformatician for Oligonucleotide therapeutics, you’ll be using bioinformatics and machine learning to identify and deliver oligonucleotide sequence designs. You will be responsible for developing and internalizing appropriate algorithms, techniques, and datasets to advance our ability to rapidly discover oligonucleotide candidate drugs.
You will also enhance our data analysis capabilities on complex, high-dimensional omics data to identify biologically induced effects of oligonucleotides. Further, you will be contributing to and leading local and global projects for NGS applied in oligonucleotide projects and ensuring that results are scientifically robust and documented.
Essential for the role
- PhD, or equivalent, in bioinformatics, mathematics, computer science, statistics, engineering, or the life sciences
- Expertise and experience in therapeutic oligonucleotide sequence design and analysis
- Expertise in DNA/RNA sequence analysis, next-generation sequencing analysis, multivariate and/or high-dimensional omics data analysis
- Experience with relevant software tools such as R and/or Python
- Proficiency in a Linux environment, experience with shell scripting and standard command line tools
- Understanding of molecular biology, cell biology, and human physiology, ontologies, data management, machine learning, statistical modeling
- Experience with tools for reproducible research such as git, conda, Snakemake or Nextflow
- Excellent English, spoken and in writing
Keywords: Senior Bioinformatician, Oligonucleotide Therapeutics, Bioinformatics, Machine Learning, Sweden, Gothenburg, AstraZeneca. AstraZeneca Hiring: Senior Role in Oligonucleotide Therapeutics in Sweden!
