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Biogen Intern Protein Development – Apply Online Now

Biogen Intern Protein Development – Apply Online Now

Intern, Protein Development

Company: Biogen

Location: Triangle, NC

About the job

Company Description

About Biogen:

At Biogen, our mission is clear – we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population.

We at Biogen are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients who we serve. We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included.

As an intern or co-op at Biogen, you can expect to be placed on a real project, under the guidance of experienced professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.

Job Description


This application is for a 12-week internship role from June – August 2024. Resume review begins in January 2024.

The downstream drug substance pilot group is responsible for pilot scale execution of downstream unit operations, prior to scaling up to manufacturing. The downstream Pilot group develops and supports the development of several of the unit operations that will make up the final purification process for a biologic therapeutic.

Position Description

As the intern, you will support the development and evaluation of the Repligen TangenX – NovaSep Sius (Hystream 30 kD) Ultrafiltration/Diafiltration (UFDF) filter to reduce COG’s in manufacturing downstream processes. You will focus on evaluating TangenX TFF filters as a potential alternative to the Millipore Pellicon Ultracel filters across multiple programs / processes.

Detailed Description Of Role Including But Not Limited To

  • Requesting downstream process intermediate samples from pilot runs and manufacturing batches.
  • Conducting and documenting small scale and pilot scale TFF experiments with a focus on process definition and understanding, assisting in experimental design and troubleshooting, and analyzing data including process modeling and proof-of-concept analyses.
  • Evaluating HySteam TangenX UFDF filter performance and cleanability/membrane regeneration side-by-side with Ultracel filters.
  • Authoring a summary report of the data as well as a presentation



  • Knowledge and technical experience in protein purification / biotechnology related filtration development
  • Familiarity with the UFDF unit operation is desirable.
  • A strong grasp of Excel and higher-level math (calculus) is desirable for this position.
  • Excellent verbal and written communication skills, time management, and organizational skills.
  • Excellency in working with PC based computer systems and relevant applications including Microsoft Word, Excel, and PowerPoint.

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:

  • Legal authorization to work in the U.S.
  • At least 18 years of age prior to the scheduled start date
  • Be currently enrolled in an accredited college or university.


  • Exceptional undergraduate student who has completed at least three years of program, or a first year Master’s program, with 0-2+ years’ experience desired
  • Desired majors include: Bio/Chemical Engineering, Biomanufacturing, or related field


Research Triangle Park, NC


Keywords: Biogen Intern Protein Development – Apply Online Now



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