Life Sciences PhD at Helmholtz Munich, Germany | Apply Now
As global urbanization and industrialization continue to reshape our environment, allergic diseases have surged into one of the most prevalent chronic illnesses of our time. If you are driven to uncover the molecular roots of this global health challenge, the Institute of Allergy Research (IAF) at Helmholtz Munich is offering a highly impactful Life Sciences PhD position. Based in Neuherberg, this PhD in Munich is a unique opportunity to join the fight against asthma, atopic dermatitis, and food allergies through cutting-edge B cell immunology.
- Position: PhD candidate (f/m/x) in B cell Immunology
- Location: Neuherberg near Munich
About The Institute
Helmholtz Munich is a premier research institution dedicated to developing groundbreaking solutions for a healthier society. In this role, you will be joining the Molecular Immunology group, led by Dr. Lesly Calderon, within the Institute of Allergy Research (IAF). The IAF operates in close collaboration with the Center of Allergy and Environment (ZAUM) at the Technical University of Munich (TUM). This partnership ensures that your Molecular Biology PhD will be grounded in both fundamental discovery and translational application. The ultimate goal is to move new ideas rapidly from the laboratory bench to real-life therapeutic interventions.
Key Research Responsibilities
B lymphocytes are at the center of the allergic response. In allergic patients, these cells are inappropriately activated and differentiate into plasma cells that secrete Immunoglobulin E (IgE)—the primary driver of allergic reactions. As a doctoral candidate, your mission is to discover new regulators of these IgE-secreting cells.
- CRISPR/Cas9 Screening: You will contribute to the development of sophisticated in vivo and in vitro CRISPR/Cas9 screening systems designed to uncover novel regulators of IgE-mediated B cell responses.
- Molecular Exploration: Once these novel regulators are identified, you will dive deep into exploring their underlying molecular mechanisms and functional roles.
- Advanced Methodologies: You will utilize a wide array of techniques, encompassing molecular biology, cell biology, biochemistry, and state-of-the-art single-cell analysis technologies.
- Animal Models: A significant portion of this Life Sciences PhD will require the handling of mice to conduct in vivo immunological studies.
- Scientific Communication: You will plan experiments, analyze complex data, draft scientific publications, and present your findings at international seminars and conferences.
Qualifications & Mindset Required For Life Sciences PhD
To thrive in this Molecular Biology PhD, you must possess a strong theoretical foundation paired with practical laboratory agility. Helmholtz Munich is looking for a scientifically curious and creative researcher.
- Educational Foundation: A Master’s degree in Molecular Biology, Biomedical Sciences, Genetics, Biochemistry, or a closely related discipline. This degree must qualify you to enroll as a PhD student at the Technical University Munich (TUM), School of Medicine and Health.
- Technical Expertise: Practical scientific expertise in fields such as immunology, genetics, epigenetics, or biochemistry.
- In Vivo Experience: A strong interest in—and willingness to perform—research using mice as animal models.
- Communication: A good command of the English language is essential for working in this international, interdisciplinary team and for writing publications.
- International Applicants: If your degree was obtained outside of Germany, you will need to request a Statement of Comparability for Foreign Higher Education Qualifications.
Compensation, Benefits & Life in Munich
Pursuing a PhD in Munich offers an exceptional blend of rigorous scientific training and high quality of life. Helmholtz Munich provides a highly supportive environment for its doctoral researchers.
- Salary Structure: Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees (EG 13 50% TV EntgO Bund), with the possibility of an additional allowance if applicable conditions are met.
- Contract Duration: The position comes with an initial fixed term of three years, with the potential for extension based on project needs.
- Academic Support: Full integration into the Helmholtz Munich Graduate School, providing access to career counseling, a dedicated Career Center, and state-of-the-art Core Facilities.
- Relocation & Integration: Access to the International Staff Service to assist with your relocation and integration process in Germany.
- Work-Life Balance: 30 days of annual leave, flexi days, public holidays, and comprehensive health promotion initiatives including sports programs and mental health resources.
Life Sciences PhD Application Details
Please send your application only via our online application tool and with the following documents:
- Cover letter
- CV
- Contact details for at least two referees
- Degrees/Diplomas/Certificates
- References from recent employers
If you have obtained a university degree abroad, further documents regarding the comparability of the degree is required.
Contact Details For Life Sciences PhD
- Name: Dr. Lesly Calderon DomÃnguez
- Email: [email protected]
In summary, this Life Sciences PhD in B cell Immunology is a premier opportunity for a young scientist looking to make a tangible impact on global health. By securing this PhD in Munich, you will gain access to world-class infrastructure, expert mentorship under Dr. Calderon, and the vibrant scientific community at TUM and Helmholtz Munich. If you are ready to leverage CRISPR technology and single-cell analysis to decode allergic diseases, this Molecular Biology PhD is the perfect launchpad for your scientific career.
