Neurocrine Biosciences Hiring postdoc Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson’s disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:
The postdoc in Gene Therapy research will participate in conducting preclinical stage Gene Therapy programs at Neurocrine using AAV vectors. Working with our Collaboration Partners and internal colleagues in Research, CMC, and Business Development, the individual will participate in work on new and existing programs.
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Your Contributions (include, but are not limited to):
The primary role is to initiate and conduct a novel Gene Therapy research project
Design and perform in vitro and in vivo studies in support of current and future Gene Therapy opportunities
Prepare data summaries and present results to peers and colleagues at Neurocrine
Be able to present data as appropriate at scientific meetings at the National and International level
Other tasks as assigned
Specific Requirements:
- Ph.D. degree in biology, life sciences or related discipline, with experience in the biotech/pharmaceutical industry OR with prior non-industry postdoc experience
- Experience with the application of gene therapy methods to animal experimental disease models. This includes experience with viral (preferably AAV) and/or non-viral gene delivery for upregulation of gene expression, downregulation, genome-editing or delivery of genetic material via lipid nanoparticles
- Knowledge about AAV vector design, capsid/cargo, serotypes, promoters, enhancers
- Experience or exposure to neuro-endocrinology or metabolism research will be a plus
Requirements:
- General knowledge about the function of the central and autonomic nervous systems and gastrointestinal system
- Experience in advanced experimental technologies and their utilization in the drug discovery process
- Experience with primary neurons and iPSC-derived neurons, and their use in assay development a plus
- In vivo experience working with animal models of disease
Excellent critical analysis skills
Assimilates data and research findings outside of Neurocrine for application to new scientific projects
Maintains broad knowledge of scientific principles and theories and possesses intellectual mastery of one or more scientific areas
Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools
Ability to work as part of teams
Excellent computer skills
Excellent communications, problem-solving, analytical thinking skills
Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
Neurocrine Biosciences Hiring postdoc
