Scripps Research Postdoc – tRNA Synthetase & β-Cells, La Jolla, California
Scripps Research seeks a motivated postdoctoral researcher for this Scripps Research postdoc opportunity in La Jolla, California. Eligible candidates must hold a PhD in a related field. Apply online via LinkedIn.
Job Details
Position: Postdoctoral Associate
Department: Integrative Structural and Computational Biology
Location: La Jolla/San Diego, California, USA
Scripps Postdoctoral Researcher Project Details
The Xiang-Lei Yang Lab is seeking a motivated postdoctoral researcher to investigate how a tRNA synthetase links nutrient sensing to translational control in pancreatic beta-cells. This Scripps postdoctoral researcher role aims to define the mechanisms of translational control that let cells adapt to metabolic stress, focusing on pancreatic beta-cells and insulin-responsive tissues, by integrating mouse models, primary cells and tissues, and multi-omics approaches, to uncover fundamental mechanisms of metabolic regulation and diabetes.
Key Responsibilities
- Investigate cellular responses to metabolic stress using mouse models and primary cells.
- Define molecular mechanisms of translational regulation through biochemical assays, polysome profiling, and integrated omics.
- Design and lead experiments, analyze data, publish findings, present at scientific meetings, and mentor junior researchers.
Eligibility Criteria
PhD in molecular biology, cell biology, biochemistry, physiology or a related field (a pending doctorate may be considered with approval of the PI and HR).
Required Skills
- Experience with mouse models, primary tissues or metabolic phenotyping.
- Islet biology, diabetes or metabolism research.
- tRNA synthetases, RNA biology or translational control.
- Translation assays such as polysome or ribosome profiling.
- Transcriptomic and proteomic data analysis.
Salary
Starting range of USD 70,304 to 75,353 per year following NIH and California exempt salary guidelines.
How to Apply
For this Scripps postdoctoral researcher position, include a cover letter, CV and contact information for three references. Full details and the apply button are on the LinkedIn job listing.
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