Scientist Job at Novartis Careers
Join Novartis Careers, one of the worldโs leading biopharmaceutical companies, as a Scientist in Upstream/Cell Culture. Based in Durham, North Carolina, this Scientist Job role focuses on the development, optimization, and scale-up of cell and gene therapy processes involving AAV and LVV production. If you are passionate about BSc Biochemistry Jobs and advancing gene therapy manufacturing and contributing to life-changing treatments, this is your opportunity to make a meaningful scientific impact.
Job Details:
- Position: Scientist, Upstream/Cell Culture
- Internal Title: Expert, Science & Technology
- Location: Durham, North Carolina, USA
- Job ID: REQ-10065927
- Date Posted: November 5, 2025
- Employment Type: Full-Time, Onsite (#LI-onsite)
- Salary Range: $93,800 โ $174,200 per year
About the Company:
Novartis is a global healthcare company reimagining medicine to improve and extend peopleโs lives. With cutting-edge research and a deep commitment to innovation, Novartis combines advanced science and technology to develop therapies that address societyโs most challenging health issues. From oncology to gene therapy, Novartis empowers scientists and engineers to transform ideas into life-saving solutions for millions worldwide.
Educational Requirements for the Scientist Job:
- Bachelorโs degree in Biochemistry, Chemical Engineering, Bioengineering, or a related field with 4+ years of experience
- OR Masterโs degree with 2+ years of experience
- OR Ph.D. with relevant academic experience (Recent Ph.D. graduates encouraged to apply)
Key Responsibilities of the Scientist Job:
- Lead and support upstream process development for cell and gene therapy (AAV/LVV) projects.
- Design and execute experiments to optimize cell culture and viral vector production.
- Apply DOE and QbD approaches for process characterization and optimization.
- Develop and scale bioreactor processes including fed-batch and perfusion systems.
- Support technology transfer and GMP manufacturing activities.
- Maintain detailed experimental records, prepare SOPs, and write technical and regulatory reports.
- Collaborate cross-functionally with R&D, analytical, and pilot-scale teams.
- Track emerging technologies and integrate innovative tools into process improvement initiatives.
- Author CMC documentation for regulatory submissions.
Skills Required for the Scientist Job:
- Hands-on experience with mammalian expression systems, bioreactors, and cell culture.
- Proficient in Design of Experiments (DoE) and statistical analysis.
- Strong understanding of upstream process development and viral vector production.
- Excellent communication, teamwork, and documentation skills.
- Organized, detail-oriented, and capable of handling multiple priorities.
- Knowledge of viral purification processes and LVV process development (preferred).
- Innovative thinker with a continuous improvement mindset.
How to Apply for the Scientist Job?
Interested applicants for the BSc Biochemistry Jobs can apply through the Novartis Careers Portal. Candidates are encouraged to create a job alert to stay informed about similar opportunities in cell and gene therapy research and manufacturing across the company.
