Allen Institute Life Science Job Opening – Scientist Post
Allen Institute Life Science. The Allen Institute for Brain Science is seeking exceptional candidates for a Scientist I position in our Seattle-based, multidisciplinary organization. The Scientist I will join the team of Hongkui Zeng and will focus on work designed to build upon our current advanced knowledge of neuronal cell types in the basal (“normal”) state to understand how cell types and circuits of the brain are modified in response to new experiences or states such as addiction.
Job Title: Scientist – Brain Science Management
Department: 1000- Allen Institute for Brain Science
Location: Seattle
Allen Institute Life Science
The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.
The work will utilize genetic tools and techniques including transgenic mice and recombinant viruses for gene delivery as well as single-cell transcriptomics. The Scientist I will also develop new techniques including behavioural paradigms to examine how important signalling pathways and molecules, such as neuropeptides, are changed in addiction-relevant regions of the brain such as the basal ganglia, amygdala and hypothalamus. Good judgment and excellent problem-solving skills are required to plan, design, execute and analyze experiments to answer novel questions of high relevance and impact to the field.
Essential Duties for Allen Institute Life Science
- Collaborate with scientists to develop new behavioral paradigms and leverage existing multi-modal data generation pipelines including transcriptomics to understand fundamental nervous system changes in addiction
- Use the newly generated data to define cell type and circuit-based changes in response to addiction
- Publish/present findings in peer-reviewed journals/scientific conferences
- Excellent organizational skills, attention to detail and the willingness to work in a milestone-driven atmosphere is mandatory.
Required Education and Experience
Allen Institute Life Science
- PhD in Neuroscience or a related life science discipline required
- Strong publication record
- Advanced knowledge and experience using mouse genetic tools
- Solid understanding of the principles of nervous system cell types and neuroanatomy
Collaborative, team-oriented mindset and approach - Preferred Education and Experience
- Advanced knowledge and experience with cutting edge experimental techniques such as single-cell transcriptomics, spatial transcriptomics and viral-based circuit tracing techniques
- For Allen Institute Life ScienceJob candidates should have Experience designing and executing behavioral assays to understand cell types and circuits
- Positive attitude, self-starter, demonstrated attention to detail, and ability to troubleshoot
- Outstanding oral and written communication skills
Work Environment
- Exposure and handling of laboratory animals required
- Laboratory atmosphere – possible exposure to chemical, biological or other hazardous substances
- Frequently required to sit, stand, walk, stoop, kneel or reach
- Possible exposure to BioSafety Level 2 organisms, such as recombinant viruses
Physical Demands
Allen Institute Life Science
- Occasional lifting to 30 pounds
- Fine motor movements in fingers/hands to operate computers and other office equipment; lab equipment
Position Type
This is an onsite, M-F, regular business hours position. May be required to be available outside of standard working hours (weekends and/or holidays).
