Regeneron Molecular Biology Associate Vacancy – Apply Online

Regeneron Molecular Biology Associate Vacancy – Apply Online

Regeneron is seeking scientifically passionate and motivated associates to join our dynamic neuroscience research group. This person will work both independently and as part of a team to perform hands-on research studies designed to investigate novel targets and mechanisms in neurodegenerative disorders. The primary focus of this will be Friedrich’s ataxia and motor neuron disease.

Job Title: Research Associate, Neuroscience

Location Tarrytown, NY, United States

Category Research and Development

Job Id 25146BR

Eligibility Criteria & Experience:

  • You have strong communication and presentation skills.
  • You have the ability to work both independently and collaboratively.
  • You can proactively work on multiple projects and prioritize as needed
  • To be considered for this opportunity, you must have a Bachelor’s degree with three years of experience or a Master’s Degree with one year of experience in neuroscience, biochemistry, molecular biology, biology, or a related discipline. Experience with mammalian cell cultures, primary neuronal cultures, immunocytochemistry, immunohistochemistry, SDS-PAGE, and western blotting strongly preferred. You should be comfortable working with mice and/or rats. A solid understanding of experimental design, statistical analysis, and data presentation is also required.
  • Experience within vitro and/or ex vivo examination of mitochondrial and/or lysosomal activity is a plus. Hands-on experience with iPSCs and/or mouse ES cells is highly desirable. Experience with RT-qPCR and basic cloning skills a plus.
  • Experience with fluorescent microscopy including confocal microscopy, and image analysis using Image J, Halo, or related software is desirable.
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As a Research Associate on the Neuroscience team, a typical day might include the following:

  • Designing and performing experiments to characterize in vitro and in vivo models of Friedreich’s Ataxia and screen potential therapeutic approaches in these models.
  • Conducting experiments in mice and rats, including handling, performing behavioral analysis, injecting compounds by a variety of routes, and dissecting tissues for histochemical and biochemical analysis.
  • Using a variety of cell lines including mouse ES cells, iPSC-derived neurons, and mouse primary neuronal cultures to screen therapeutics.
  • Isolating RNA from cells and mouse tissue and perform Real-time qPCR for quantification of gene changes from disease and therapeutic intervention.
  • Utilizing immunohistochemistry, biochemistry, and ELISA to profile in vitro and in vivo models of motor neuron disease and screen novel therapeutic compounds.
  • Performing data analysis on experimental data as well as troubleshooting under minimal direction.
  • Staying current on relevant literature in order to further develop scientific expertise, new assays, and expand scientific/technical knowledge and skillsets.
  • Participating in group and departmental meetings and giving presentations.
  • Contributing to the writing of protocols and articles for publication.
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