Doctoral Programs at UKE, Germany | Biological Sciences | Apply Now
The University Medical Center Hamburg-Eppendorf (UKE) is currently inviting applications for a high-impact Life Sciences PhD within its prestigious Centre for Molecular Neurobiology (ZMNH). This position is a cornerstone of the Research Unit FOR 5228 “Syntophagy,” a DFG-funded initiative dedicated to uncovering the mysteries of neuronal autophagy. As a doctoral candidate at the Institute of Neuroimmunology and Multiple Sclerosis (INIMS), you will join a world-class team investigating how immune dysregulation drives neurobiological damage in Multiple Sclerosis (MS). If you are looking for a Biological Sciences Job that bridges molecular biology with translational medicine, this Doctoral Program offers the structured supervision and international network necessary to launch a top-tier research career.
About the Institute
UKE is one of Europe’s leading university hospitals, housing approximately 16,100 employees dedicated to “comprehensive healthcare” and “excellence in research”. The Center for Molecular Neurobiology is a flagship institution for basic neuroscience in Germany, providing PhD students with access to cutting-edge core facilities. The Institute of Neuroimmunology and Multiple Sclerosis (INIMS) specializes in systems biology and advanced microscopy to track immune-cell behavior within the central nervous system. This role involves direct collaboration with immunologists, neurobiologists, and bioinformaticians, ensuring a multidisciplinary approach to every experiment.
Project Details
This Life Sciences PhD focuses specifically on the mechanisms and function of autophagy—the cell’s “self-eating” recycling process—within healthy and inflamed neurons.
- The project focuses on the mechanisms and function of autophagy in healthy and inflamed neurons of an animal model of MS.
- MS Mouse Models: You will investigate molecular neurobiological mechanisms using established animal models of Multiple Sclerosis.
- Advanced Microscopy: The role utilizes high-end technology, including confocal and superresolution microscopy, to visualize protein interactions at the sub-cellular level.
- Molecular Cloning & Biochemistry: Tasks include designing molecular constructs, managing cell cultures, and conducting biochemical assays to validate findings.
- Dissemination: You will be expected to present your research at international symposia and draft high-impact publications for journals like Nature Immunology or Cell.
Candidate Profile: Requirements for the Life Sciences PhD
UKE is seeking a highly motivated researcher with a strong background in the molecular foundations of life.
- Education: A Master’s degree or diploma in Biological Sciences, Biochemistry, Biomedical Sciences, or a related Life Sciences field.
- Technical Skills: Practical experience in basic cell biology, molecular techniques, and microscopy is required.
- Preferred Assets: Candidates with FELASA B certification (for animal handling) and basic knowledge of Bioinformatics (R) will be given priority.
- Language Proficiency: Excellent command of both spoken and written English is essential for this internationally oriented curriculum.
- Immunity Status: Applicants must provide proof of measles immunization before employment begins.
Diversity and Inclusion at UKE: By the Numbers
UKE explicitly values variety and is a signatory of the Charter of Diversity. To provide a concrete look at their progress and goals:
- Gender Distribution: Approximately 65% of the total workforce at UKE is female. However, as noted in the job posting, there is an explicit aim to increase the proportion of women in management and scientific leadership positions.
- Internationality: UKE employs staff from over 90 different nations, reflecting its role as a global hub for medical research.
- Inclusion Policy: Persons with severe disabilities are given priority if they possess equal aptitude and professional performance.
Offer and Logistics: Doctoral Program Benefits
- Compensation: Attractive pay according to the TVöD/VKA scale (at 65% of regular weekly working hours).
- Contract: Initially limited to four years, providing long-term stability for the duration of the PhD.
- Family Support: Includes vacation childcare, advice for relatives in need of care, and cooperation on long-term childcare solutions.
- Sustainable Travel: Subsidies for the Deutschlandticket and access to the “Dr. Bike” bicycle service.
- Start Date: The position is available immediately, with a preferred start in early summer 2026.
Contact Details
- Prof. Dr. Manuel Friese // Dr. Maria Andres-Alonso
- Email:
In summary, this Research Fellow/PhD position within the “Syntophagy” Research Unit is a premier Doctoral Program for those passionate about the intersection of the immune system and the brain. By joining UKE Hamburg, you gain access to a “secure employment” environment that prioritizes your work-life balance while pushing the boundaries of what is possible in MS research. Because the project is already third-party funded and integrated into a structured graduate school, you will have the financial and academic support required to transition from a student to a high-impact Biological Sciences Job professional.
