Biologist Job at Lilly USA
Looking for a senior-level Biologist Job in the USA with a world-renowned pharmaceutical company? This Neurodegeneration Job at Lilly Careers in Indianapolis offers a powerful opportunity to work at the forefront of CNS drug discovery. Ideal for professionals and job opportunities for life science graduates with industry experience, this role combines cutting-edge in vivo research, blood-brain barrier science, and real-world impact on neurodegenerative diseases.
About the Company
Eli Lilly and Company is a global pharmaceutical leader headquartered in Indianapolis, USA. Through Lilly Careers, scientists and researchers work to discover life-changing medicines, advance disease understanding, and improve global health. Lilly’s culture blends innovation, integrity, and community impact, making it a top destination for Jobs in USA within life sciences.
Job Details:
- Job Title: Sr. Biologist – Neurodegeneration
- Company: Eli Lilly and Company
- Location: Indianapolis, Indiana, United States of America
- Category: Research & Development
- Job Type: Full-Time, Regular
- Job ID: R-100190
Key Objectives / Deliverables
- Design, lead, and conduct in vivo studies evaluating blood–brain barrier (BBB) penetration and efficacy of novel therapeutics for neurodegenerative diseases
- Manage studies from initiation through data delivery, including execution of core in vivo dosing techniques and tissue collection
- Perform study-specific workflows focused on BBB characterization, including pharmacokinetic sampling, brain and plasma collection, and biodistribution analysis
- Conduct rodent RNA isolations, RT-qPCR, and biochemical assays (ELISA, Western blotting, protein quantification) to assess target engagement and pharmacodynamic responses in brain tissue
- Maintain accurate and well-organized experimental records, protocols, and sample inventories using electronic lab notebooks
- Communicate study progress, BBB penetration data, and pharmacological findings to project leads and cross-functional teams
- Ensure compliance with IACUC-approved animal protocols and uphold high standards of animal welfare and laboratory safety
Basic Requirements For Biologist Job in USA
- Bachelor’s or Master’s degree in Biology, Neuroscience, or a related field
- Experience:
- 1–2 years of industry experience with a Bachelor’s degree, or
- 0–1 years of industry experience with a Master’s degree
- Authorization to work in the United States on a full-time basis
- Lilly will not provide sponsorship or support for work authorization or visas, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1
Additional Skills / Preferences
- Experience with biochemical assays (ELISA, Western blotting, protein quantification)
- Experience with rodent RNA isolations and RT-qPCR
- Hands-on experience in rodent handling, dosing, and tissue collection
- Ability to work independently and collaboratively within multidisciplinary research teams
- Strong attention to detail, time management, and record-keeping skills
- Experience with CSF collection, ICV injections, or stereotaxic surgeries
- Familiarity with blood–brain barrier permeability studies or CNS drug delivery approaches
- Working knowledge of neurodegenerative disease models (e.g., Alzheimer’s, Parkinson’s, ALS)
- Background in drug discovery or preclinical development, particularly CNS therapeutics
- Experience with pharmacokinetic or biodistribution studies in the CNS
- Strong documentation, communication, and data presentation skills


