Life Sciences Job at Syneos Health, USA | Project Manager | Apply Now
The landscape of clinical operations is shifting rapidly, and few sectors are evolving faster than advanced therapeutics. If you are a clinical project management professional looking to position yourself at the absolute forefront of oncology innovation, this Project Manager I – Cell & Gene Therapy role with Syneos Health is an incredible career move. Operating as a sponsor-dedicated position, this unique Life Sciences Job offers the agility of working directly with a biotech leader alongside the robust global infrastructure of a top-tier CRO. It is a highly strategic opportunity to advance your path within Syneos careers while working on groundbreaking CAR-T and gene-modified cell therapies.
- Job Position: Project Manager I – Cell & Gene Therapy (Sponsor Dedicated – US Remote; Preference for Los Angeles, CA)
- Location: United States
About the Company
Syneos Health is a leading, fully integrated life sciences services organization built to accelerate drug development. What makes this specific role stand out is its “Sponsor Dedicated” design. Syneos Health® is a premier, multinational life sciences services organization designed specifically to accelerate the clinical development and commercial success of modern therapies. Headquartered in Morrisville, North Carolina, it stands out as the industry’s only fully integrated biopharmaceutical solutions organization, seamlessly blending a top-tier Contract Research Organization (CRO) with a powerhouse Contract Commercial Organization (CCO).
Life Sciences Job – Key Responsibilities
In this position, you will serve as a sponsor-facing project manager, ensuring the flawless execution of early-phase CAR-T and gene therapy clinical trials from startup through database lock.
Your day-to-day operations will center around these core targets:
- Study & Site Activation: Lead and support critical study start-up, site activation, and patient enrollment milestones, collaborating closely with site monitors and regulatory personnel.
- Cross-Functional Liaison: Serve as the central point of contact across internal CRO teams and the biotech sponsor, facilitating routine governance updates and precise status reporting.
- Timeline & Budget Tracking: Coordinate with diverse stakeholders to ensure complex, high-touch trial milestones, budgets, and operational timelines are met flawlessly.
- Quality & Protocol Compliance: Track and manage site-level quality indicators, drive Corrective and Preventive Actions (CAPAs), and proactively resolve internal or external audit findings.
- Inspection Readiness: Maintain absolute regulatory compliance by overseeing electronic Trial Master File (eTMF) currency, data accuracy, and overall documentation completeness.
- Logistical Overwatches: Contribute to the tracking and handling of low-stability endpoint samples and investigational product (IP) processes, ensuring time-critical laboratory deliveries.
- Risk Mitigation: Proactively identify trial operational risks, develop mitigation frameworks, and continuously optimize trial execution protocols.
Qualifications & Skills Required For Life Sciences Job
Because cell and gene therapy trials feature intense logistical complexity (such as managing low-stability cellular payloads), Syneos requires a solid foundation in specialized clinical research.
- Educational Foundation: A Bachelor’s degree in a relevant field (such as Life Sciences or a related scientific discipline) or equivalent clinical work experience.
- Targeted Experience: 2 to 4 years of hands-on clinical trial experience, preferably within a CRO or pharma setting, with a clear focus on oncology, rare diseases, or gene-modified cell therapies.
- Therapeutic Familiarity: Prior operational involvement or familiarity with CAR-T pipelines or cellular processing is highly desirable for this Life Sciences Job.
- Regulatory Fluency: Strong, working familiarity with GCP/ICH guidelines, FDA/EMA regulations, and standard inspection-readiness frameworks.
- Systems Mastery: High proficiency navigating standard clinical trial architecture, including CTMS, EDC, and eTMF platforms.
- Communication Strength: Confident leading high-stakes sponsor calls, presenting core performance KPIs, and contributing meaningfully to corporate governance.
In summary, this Project Manager I position is a masterclass in modern clinical trial design. By taking on this role, you position your scientific profile at the absolute cutting edge of oncology, mastering the complex supply chain and regulatory environments that cell therapies demand. If you possess a life sciences background, 2+ years of oncology or CRO experience, and are ready to advance breakthrough science from your remote office, apply today to secure this standout position among clinical Jobs in USA and fast-track your Syneos careers trajectory.
